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Latest San Francisco 49ers News

49ers vs. Buccaneers: Where to watch NFL Week 6, betting odds, promos, score prediction for Jones vs. Mayfield
October 11th 2025
How to bet Buccaneers vs. 49ers in the NFL Week 6 matchup on Paramount+  full article
NFL insider expects 49ers to have trade interest in $29 million star edge rusher
October 11th 2025
The Athletic's Dianna Russini revealed on Saturday that she expects the San Francisco 49ers to have trade interest in Cincinnati Bengals edge rusher Trey Hendrickson.  full article
49ers vs Buccaneers Predictions, Picks & Best Bets for NFL Week 6
October 10th 2025
Get the best 49ers vs. Buccaneers predictions ahead of Sunday's huge NFC showdown. Free NFL picks for October 12.  full article
NFL Week 6 betting: Expert backs Bills in money line favorites parlay while locking 49ers in underdog parlay
October 10th 2025
SportsLine expert Jeff Hochman dishes his top money line parlays for favorites and underdogs for Week 6 of the NFL season  full article
49ers vs. Buccaneers odds, start time: Everything you need to crush your 2025 NFL Week 6 picks
October 9th 2025
The SportsLine Projection Model has revealed its San Francisco vs. Tampa Bay picks for the 2025 NFL Week 6 contest  full article
NFL Week 6 picks: Lions upset Chiefs; Buccaneers beat 49ers
October 9th 2025
Sam Farmer makes his picks and predictions for Week 6 of the NFL season, with the Lions defeating the Chiefs in prime time and the Seahawks improving to 4-2.  full article
NFL makes 49ers' Eddy Pineiro announcement after upset win over Rams
October 8th 2025
The 49ers might've finally found their new kicker.  full article
Faithful share their biggest concern about 49ers' 2025 NFL season so far
October 7th 2025
NBC Sports Bay Area asked 49ers fans what worries them the most about San Francisco's season so far, and their answer wasn't surprising at all.  full article
NFL Week 6 picks and score predictions: Lions stun Chiefs, 49ers upset Buccaneers in NFC showdown
October 7th 2025
Here's your weekly dose of John Breech's NFL picks  full article
NFL picks, predictions for Week 6: Bucs hold off 49ers, Lions keep rolling past Chiefs
October 7th 2025
The Sporting News' Bill Bender predicts the biggest surprises and upsets in Week 5 of the NFL season.  full article
49ers huge Week 6 game vs. Buccaneers gets top NFL broadcast team
October 7th 2025
The San Francisco 49ers and Tampa Bay Buccaneers will face off in a key NFC matchup, and CBS is bringing their top broadcast team for the game.  full article
NFL power rankings: Eagles fall as Lions, 49ers rise; Patriots, Colts Broncos ride up for Week 6
October 6th 2025
How do all 32 teams in the NFL stack up against each other coming out of Week 5 of the 2025 NFL regular season? Here's an updated look from best to worst.  full article
Questions, takeaways off every NFL Week 5 game: Would Vikings do a trip like this again? How good can these 49ers be?
October 5th 2025
Our NFL Nation reporters answer the biggest questions out of each game. Here's what we learned from Week 5.  full article

Team Leaders

Sacks
18.5 Sacks
Passing Leader
114/170, 1374 YDS, 13 TD, 4 INT
Receiving Leader
78 REC, 1015 YDS, 8 TD

49ers Team Roster for Running Back

Isaac Guerendo
Experience: 2
Height: 6' 0"
Weight: 221 lbs
Active
Jordan James
Experience: Rookie
Height: 5' 9"
Weight: 208 lbs
Out
Christian McCaffrey
Experience: 9
Height: 5' 11"
Weight: 210 lbs
Active
Brian Robinson Jr.
Experience: 4
Height: 6' 1"
Weight: 225 lbs
Active